A research assistant is sought to work on the mass spectrometric analysis of peptides and proteins with Dr Richard Kay in the Institute of Metabolic Science. The laboratory has a focus on identifying and quantifying peptides relevant to metabolic diseases, and is equipped with a high resolution Orbitrap mass spectrometer and a Waters TQ-XS triple quadrupole. The post-holder will collaborate with researchers across the IMS to develop new LC-MS/MS peptidomics and proteomics methods for quantifying proteins and peptides in tissue, cells and plasma.
The research assistant will be a member of a team researching mechanisms underlying obesity and metabolic diseases. The laboratory uses mass spectrometry to identify and measure peptides and proteins and investigate how these molecules are involved in energy metabolism and how they can affect the health of patients with metabolic diseases.
The group has two mass spectrometers which the applicant will aid in running. A ThermoFisher Q-Exactive Plus Orbitrap with an Ultimate 3000 nano LC system which is used for untargeted peptidomics and proteomics experiments. This system is used to generate proteomics and peptidomics datasets that are searched with the PEAKS Bioinformatics software package, and the results interrogated using the Perseus program. The second system is a Waters TQ-XS triple quadrupole with an M Class LC system. The instrument has a normal source interface, an IonKey source and a nano source to cater for various throughput and sensitivity requirements.
The successful applicant will have a BSc/MSc in analytical chemistry or a related field and will ideally have had experience in a laboratory environment.
Fixed-term: The funds for this post are available until 31 March 2024 in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment. This appointment also requires a Research Passport application.
We welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.
This is an integrated appointment between the University and Cambridge University Hospitals NHS Foundation Trust (“NHS Trust”). You will therefore also be issued with an Honorary Research Contract by the NHS Trust. You should be aware that if your contract with the NHS Trust is terminated your employment with the University will be terminated, and vice versa.
Closing date: 14th November 2022
Date of interviews: To be confirmed
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
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