A postdoctoral research position has become available in the laboratory of Dr Catherine Merrick, working on an ERC-funded project to study DNA replication in Plasmodium. The post will be available from June 21st 2022, and due to loss of existing staff an immediate start is preferred. The new appointee will join an active, ongoing project with two other experienced staff in-post, plus the support of a technician: there is a high probability of publishing the work at the end of the project. Although the current ERC funding is time-limited, grant applications are also underway to extend this work beyond May 2023.
The project is a continuation of our work currently in-press at Plos Pathogens: ‘DNA replication dynamics during erythrocytic schizogony in the malaria parasites Plasmodium falciparum & Plasmodium knowlesi’ McDonald, J., Merrick, C.J. (BioRxiv ).
Here, we use a cutting-edge system of nascent DNA replication labelling in Plasmodium to follow replication dynamics during the unusual cell division mode of schizogony. Having established many of these parameters, we now seek to investigate how they might change when the parasite faces challenges such as host nutritional stress or DNA-damaging antimalarial drugs. The work therefore has far-reaching implications for malaria parasite virulence.
Applicants should hold a PhD in parasitology or molecular/cellular biology.
Skills in cell culture (ideally Plasmodium culture), microscopy and the quantitative analysis of microscopy data are highly desirable. The appointee will benefit from excellent facilities, including recently-refurbished Category-3 containment laboratories at the Cambridge Pathology Department.
Closing date for applications: 14th June 2022
Interviews will be held in the week of 20th June 2022.
Fixed-term: The funds for this post are available until 31 May 2023 in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.
Informal enquiries are welcome and should be addressed to
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