Applications are invited for the role of Post-Doctoral Research Associate in Translational Neurooncology to work in the Hamerlik lab in Manchester. Working as part of a multidisciplinary team, the successful applicant will be responsible for driving the interrogation of molecular targets associated with glioblastoma recurrence. In particular, the post-doctoral research fellow will study mechanisms driving aberrant DNA repair and its functional interplay with DNA replication and transcription. The project will involve multi-omic profiling (scRNAsequencing, spatial proteomics and MSI) and utilize unique patient-derived spheroid and xenograft models developed in our laboratory for down-stream proof-of-mechanism experiments.

The successful applicant will have their PhD or equivalent in biology and must have relevant laboratory experience in molecular, cellular and tumour biology. They should have demonstrable experience in defining and solving their own research questions as they will be expected to take a lead in planning and organising study activities, supported by the Principal Investigator. There will be opportunities to lead and contribute to publications and present findings at national conferences.

The post holder will be based at the Ogelsby Cancer Research Building in Manchester. The role will be highly collaborative; it will involve working together with colleagues across cancer sciences, but also more broadly.

The project is supported by the Brain Tumour Charity grant and will be supervised by Prof. Petra Hamerlik, Chair of Translational Neuro-Oncology at the University of Manchester.

The University of Manchester values a diverse workforce and welcomes applications from all sections of the community.

The School/Department is strongly committed to promoting equality and diversity, including the Athena SWAN charter for gender equality in higher education. The School/Department holds a Silver Award which recognises their good practice in relation to gender; including flexible working arrangements, family-friendly policies, and support to allow staff achieve a good work-life balance. We particularly welcome applications from women for this post. All appointment will be made on merit.